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Enhancing transcription–replication conflict targets ecDNA-positive cancers – Nature

Antibodies and reagents Antibodies Antibodies were procured from the following: H3K36me3 (Abcam, catalogue no. ab9050), γH2AX (Millipore, catalogue no. 05-636 for IF), γH2AX (Cell Signaling Technology, catalogue no. CST9718 for western blot), pRPA2S33 (Novus Biological, catalogue no. NB100-544), pCHK1S345 (Invitrogen, catalogue no. PA5-34625), 53BP1 (Novus Biological, catalogue no. NB100-304), cyclin A (BD Biosciences, catalogue no. […]