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Week 10 of the 2024 NFL regular season is on the immediate horizon and it will begin with Thursday Night Football between the Cincinnati Bengals and Baltimore Ravens in a massive AFC North clash. The Bengals should’ve beaten Baltimore a few weeks back, and a win for Joe Burrow and company would go a long way in the race for that division, and a playoff spot in a crowded AFC. Additionally, one of the more intriguing contests of Sunday’s slate pits the Philadelphia Eagles against the Dallas Cowboys in a game that could effectively serve as an elimination game for Dallas.
Make sure you check out our NFL predictions as we add our picks on the side and total for every game throughout the week – and throughout the entire season. Also, make sure to check out our NFL best bets page for our top picks. For now, let’s break down the NFL Week 10 opening lines and give our best early bet to make.
NFL Week 10 opening lines and odds
Odds available at FanDuel Sportsbook at time of publishing
- Cincinnati Bengals +6.5 (-110) vs Baltimore Ravens -6.5 (-110) – Thursday Night Football
- New York Giants -5.5 (-110) vs Carolina Panthers -3 (-110)
- New England Patriots +6.5 (-105) vs Chicago Bears -6.5 (-115)
- Buffalo Bills -4.5 (-115) vs Indianapolis Colts +4.5 (-105)
- Minnesota Vikings -4.5 (-115) vs Jacksonville Jaguars +4.5 (-105)
- Denver Broncos +9.5 (-104) vs Kansas City Chiefs -9.5 (-118)
- Atlanta Falcons -3 (-115) vs New Orleans Saints +3 (-105)
- San Francisco 49ers -6.5 (-110) vs Tampa Bay Buccaneers +6.5 (-110)
- Pittsburgh Steelers +2.5 (-110) vs Washington Commanders -2.5 (-110)
- Tennessee Titans +8.5 (-110) vs Los Angeles Chargers -8.5 (-110)
- New York Jets +1.5 (-105) vs Arizona Cardinals -1.5 (-115)
- Philadelphia Eagles -6.5 (-115) vs Dallas Cowboys +6.5 (-105)
- Detroit Lions -4.5 (-110) vs Houston Texans +4.5 (-110) — Sunday Night Football
- Miami Dolphins +2.5 (-110) vs Los Angeles Rams -2.5 (-110) — Monday Night Football
Best bet for NFL Week 10: Cincinnati Bengals +6.5 (-110) vs Baltimore Ravens
This is easily the most important game of the Bengals’ season to date, and I think we’re getting a few points of value on Zac Taylor’s team considering their uninspiring 4-5 record. With that said, I think this is a great matchup for Burrow and the Cincinnati offense, as we just saw in the previous meeting between these teams on October 6. While the Ravens ultimately prevailed by a score of 41-38 in that game, it took the Bengals botching a field goal in overtime for that to happen. In that matchup, Burrow torched a Ravens defense that ranks inside the bottom quarter of the league in defending the pass, as the LSU product threw for 392 yards and 5 touchdowns. Historically, Burrow thrives in this spot, as he’s a whopping 16-3 as an underdog of 3 or more points. Lamar Jackson has also fared very poorly in this role as a home favorite between 3 and 10 points (28% against the spread), so let’s back the Bengals catching nearly a full touchdown while we still can.
We’ll have NFL Week 10 picks for every game!